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Martin J B Taphoorn Selected Research

Procarbazine (Matulane)

10/2022Joint Final Report of EORTC 26951 and RTOG 9402: Phase III Trials With Procarbazine, Lomustine, and Vincristine Chemotherapy for Anaplastic Oligodendroglial Tumors.
1/2020Calculating the net clinical benefit in neuro-oncology clinical trials using two methods: quality-adjusted survival effect sizes and joint modeling.
4/2015Joint modeling of longitudinal health-related quality of life data and survival.
1/2014Health-related quality of life and cognitive functioning in long-term anaplastic oligodendroglioma and oligoastrocytoma survivors.
11/2013New clinical, pathological and molecular prognostic models and calculators in patients with locally diagnosed anaplastic oligodendroglioma or oligoastrocytoma. A prognostic factor analysis of European Organisation for Research and Treatment of Cancer Brain Tumour Group Study 26951.
1/2013Adjuvant procarbazine, lomustine, and vincristine chemotherapy in newly diagnosed anaplastic oligodendroglioma: long-term follow-up of EORTC brain tumor group study 26951.
3/2010IDH1 and IDH2 mutations are prognostic but not predictive for outcome in anaplastic oligodendroglial tumors: a report of the European Organization for Research and Treatment of Cancer Brain Tumor Group.
12/2009MGMT promoter methylation is prognostic but not predictive for outcome to adjuvant PCV chemotherapy in anaplastic oligodendroglial tumors: a report from EORTC Brain Tumor Group Study 26951.
12/2007Health-related quality of life in patients treated for anaplastic oligodendroglioma with adjuvant chemotherapy: results of a European Organisation for Research and Treatment of Cancer randomized clinical trial.
6/2006Adjuvant procarbazine, lomustine, and vincristine improves progression-free survival but not overall survival in newly diagnosed anaplastic oligodendrogliomas and oligoastrocytomas: a randomized European Organisation for Research and Treatment of Cancer phase III trial.

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Martin J B Taphoorn Research Topics

Disease

36Neoplasms (Cancer)
10/2022 - 11/2002
34Glioma (Gliomas)
11/2022 - 08/2002
22Brain Neoplasms (Brain Tumor)
12/2022 - 07/2002
15Epilepsy (Aura)
11/2022 - 10/2003
15Glioblastoma (Glioblastoma Multiforme)
01/2020 - 03/2005
9Oligodendroglioma
01/2020 - 06/2006
8Death (Near-Death Experience)
11/2022 - 01/2014
8Seizures (Absence Seizure)
11/2022 - 12/2003
6Neoplasm Metastasis (Metastasis)
08/2021 - 07/2002
5Fatigue
09/2021 - 10/2013
5Cognitive Dysfunction
05/2021 - 03/2004
4Meningioma (Meningiomas)
01/2022 - 11/2017
4Astrocytoma (Pilocytic Astrocytoma)
01/2020 - 06/2006
3Melanoma (Melanoma, Malignant)
09/2012 - 11/2002
2Lymphoma (Lymphomas)
08/2021 - 10/2010
2Vomiting
01/2020 - 12/2007
2Nausea
01/2020 - 12/2007
2Necrosis
11/2019 - 11/2013
2Infections
11/2016 - 08/2014
2Thrombocytopenia (Thrombopenia)
09/2014 - 08/2014
1Pain (Aches)
01/2022
1Edema (Dropsy)
01/2021
1Chronic Hepatitis B
11/2016
1HIV Infections (HIV Infection)
11/2016
1Virus Diseases (Viral Diseases)
11/2016
1Lymphopenia (Lymphocytopenia)
09/2014
1Neutropenia
09/2014
1Disease Progression
09/2014
1Hypertension (High Blood Pressure)
08/2014
1Residual Neoplasm
11/2013
1Status Epilepticus (Complex Partial Status Epilepticus)
11/2013
1Central Nervous System Diseases (CNS Diseases)
09/2012
1Stroke (Strokes)
06/2011
1Neurologic Manifestations (Neurological Manifestations)
06/2011
1Migraine Disorders (Migraine)
06/2011
1Headache (Headaches)
06/2011
1Leukoencephalopathies
06/2011
1Brain Diseases (Brain Disorder)
10/2010
1Viral Meningitis
09/2006

Drug/Important Bio-Agent (IBA)

20Temozolomide (Temodar)FDA LinkGeneric
01/2022 - 03/2005
17Anticonvulsants (Antiepileptic Drugs)IBA
12/2022 - 10/2003
12Lomustine (CCNU)FDA Link
10/2022 - 06/2006
10Procarbazine (Matulane)FDA Link
10/2022 - 06/2006
10Vincristine (Oncovin)FDA LinkGeneric
10/2022 - 06/2006
6Bevacizumab (Avastin)FDA Link
01/2022 - 08/2014
4Levetiracetam (Keppra)FDA LinkGeneric
11/2022 - 01/2021
4Isocitrate Dehydrogenase (Isocitrate Dehydrogenase (NAD+))IBA
01/2020 - 11/2013
3Valproic Acid (Depakote)FDA LinkGeneric
11/2022 - 01/2021
2BenzodiazepinesIBA
11/2022 - 04/2016
2LacosamideFDA Link
11/2022 - 08/2021
24-amino-4'-hydroxylaminodiphenylsulfone (HADS)IBA
05/2021 - 08/2020
2Biomarkers (Surrogate Marker)IBA
01/2020 - 01/2016
2ErbB Receptors (EGF Receptor)IBA
01/2020 - 03/2009
2Midazolam (Versed)FDA LinkGeneric
04/2016 - 01/2014
2IntegrinsIBA
09/2014 - 04/2006
2Proteins (Proteins, Gene)FDA Link
09/2006 - 11/2003
2GadoliniumIBA
10/2005 - 06/2004
1perampanelIBA
11/2022
1Angiogenesis InhibitorsIBA
01/2022
1Pregabalin (Lyrica)FDA Link
10/2021
1Phenytoin (Dilantin)FDA LinkGeneric
10/2021
1TabletsIBA
09/2021
1Lamotrigine (Lamictal)FDA LinkGeneric
08/2021
1Telomerase (Telomerase Reverse Transcriptase)IBA
01/2020
1Indicators and Reagents (Reagents)IBA
01/2019
1vasectrin IIIIBA
01/2018
1mesoglycanIBA
11/2017
1MethyltransferasesIBA
10/2016
1DNA (Deoxyribonucleic Acid)IBA
10/2016
1temsirolimusFDA Link
10/2016
1CilengitideIBA
09/2014
1Pharmaceutical PreparationsIBA
01/2014
1Clonazepam (Rivotril)FDA LinkGeneric
01/2014
1antineoplaston A10 (A 10)IBA
11/2013
1Modafinil (Provigil)FDA Link
10/2013
1ParaffinIBA
12/2009
1Biological ProductsIBA
12/2009
1Formaldehyde (Formol)FDA Link
12/2009
1Carmustine (FIVB)FDA Link
03/2009
1epidermal growth factor receptor VIIIIBA
03/2009
1Erlotinib Hydrochloride (CP 358,774)FDA Link
03/2009
1ChemokinesIBA
09/2006

Therapy/Procedure

37Radiotherapy
11/2022 - 07/2002
24Drug Therapy (Chemotherapy)
11/2022 - 07/2002
10Therapeutics
01/2020 - 12/2003
6Palliative Care (Palliative Therapy)
12/2020 - 01/2014
5Aftercare (After-Treatment)
01/2022 - 12/2007
5Chemoradiotherapy
01/2020 - 08/2014
4Cognitive Training
09/2021 - 08/2009
3Activities of Daily Living (ADL)
08/2021 - 07/2013
2Immunotherapy
10/2021 - 01/2020
2Combined Modality Therapy
11/2016 - 11/2010
2Terminal Care (Care, Terminal)
01/2015 - 11/2010
1Precision Medicine
11/2019
1Proton Therapy
11/2019
1Oral Administration
11/2016
1Therapeutic Abortion
11/2013
1Life Support Care
01/2012
1Adjuvant Chemotherapy
12/2007
1Salvage Therapy
10/2006